Non-toxic melanin production inhibitors from Garcinia livingstonei (Clusiaceae)
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چکیده
منابع مشابه
Non-toxic melanin production inhibitors from Garcinia livingstonei (Clusiaceae).
ETHNOPHARMACOLOGICAL RELEVANCE The stem bark of Garcinia livingstonei is used traditionally as a skin lightening agent. AIM OF THE STUDY To isolate and identify compounds responsible for the observed skin lightening activity of Garcinia livingstonei and to evaluate their cytotoxicity. MATERIALS AND METHODS Constituents of the stem bark and fruits of Garcinia livingstonei were isolated using...
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Amentoflavone and 4' monomethoxy amentoflavone were previously isolated from Garcinia livingstonei leaves. These compounds had good activities (MIC 6 and 8 μg/ml) against some nosocomial bacteria. In this study, the activity of these purified compounds were tested against fast-growing non-pathogenic Mycobacterium smegmatis. Amentoflavone was the most active compound, with an MIC of 0.60 ± 0.70 ...
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Benzophenones from natural sources and those of synthetic analogues present several reports of potent biological properties, and Guttiferone A represents a promising medicinal natural compound with analgesic and gastroprotective profiles. Considering that there are no reports that assess the genetic toxicity of Guttiferone A, the present study was undertaken to investigate the genotoxic potenti...
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ژورنال
عنوان ژورنال: Journal of Ethnopharmacology
سال: 2013
ISSN: 0378-8741
DOI: 10.1016/j.jep.2013.07.023